Disease Elimination and Eradication
This priority area is focused towards the reduction of new cases of an infectious disease, or the complete and permanent eradication of worldwide cases to zero. IEPI strategizes to tackle infectious disease management, control and elimination strategies that raise ethics and policy issues in the global health landscape.
Gene Drive: Use of gene drive mosquitoes to target anopheles mosquitoes for malaria eradication.
Controlled Human Infection Models: The deliberate infection of healthy participants with disease-causing pathogens sparks ethical concerns. IEPI is leading the way in developing tools to standardize the field of CHIM research and strengthen the regulatory environment within which this model of research sits.
Microfilaricides - Lymphatic Filariasis & Onchocerciasis: Examining the moral considerations and justification of whether single-dose combination therapy with ivermectin, DEC and albendazole is a safer and more efficacious treatment for LF and onchocerciasis than currently approved regimens of albendazole & DEC.
Human Papilloma Virus: New evidence suggests that a single-dose of HPV vaccine may provide similar efficacy to the currently licensed two-dose regimen in girls aged 9-18 years. IEPI is investigating the ethical justifiability of a one-dose HPV vaccine initiative which may have a greater health impact.